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Central Yharnam

The first city district: meet the window survivors, take the sewer route to the Saw Hunter Badge, and defeat the Cleric Beast on the Great Bridge.
Young Girl: agree to find her motherQuest stepMissablePoint of no return
Location
Central Yharnam · Window at the top of the ladder back to the fountain plaza
Why you can lose it
Her questline has to be started before Nightfall (after Vicar Amelia and Laurence's skull).
Point of no return
Examining Laurence's skull after Vicar Amelia moves the world to Night. Before you do, make sure you have started the Young Girl's quest, spoken to Eileen outside Oedon Chapel, cooperated with Alfred and claimed Gilbert's Flamesprayer.
Summary
Agree to look for her mother and she gives you the Tiny Music Box, which briefly stuns Father Gascoigne.
Sources
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Tomb of Oedon

Father Gascoigne guards the way to Cathedral Ward. His family's story starts on the rooftop beside the arena.
Young Girl: give her the broochQuest stepMissablePoint of no return
Location
Central Yharnam · Her window
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
This cycle's choice for her: hand over the brooch. She stops talking, and the ribbon steps below open up. In NG+ you send her to the clinic instead, for the other outcome.
Sources
Report an issue
Young Girl: Red Messenger Ribbon from the sewer boarQuest stepMissablePoint of no return
Location
Central Yharnam · Sewer tunnel
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Reset the area (reload or use a Hunter's Mark) after the brooch. The Maneater Boar in the sewer tunnel now drops the Red Messenger Ribbon.
Sources
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Cathedral Ward

Oedon Chapel becomes your safe haven. Unlock it, collect the early runes, and talk to everyone before Nightfall.
Alfred: offer to cooperateQuest stepMissablePoint of no return
Location
Cathedral Ward · Behind the church to Old Yharnam
Why you can lose it
If you first meet him at the Forbidden Woods gate after Nightfall, the Pray gesture from this talk is lost.
Point of no return
Examining Laurence's skull after Vicar Amelia moves the world to Night. Before you do, make sure you have started the Young Girl's quest, spoken to Eileen outside Oedon Chapel, cooperated with Alfred and claimed Gilbert's Flamesprayer.
Summary
He prays behind the church that leads down to Old Yharnam. Agree to cooperate for Fire Paper and the Pray gesture.
Sources
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Gilbert: receive the FlamesprayerQuest stepMissablePoint of no return
Location
Central Yharnam · Gilbert's window
Why you can lose it
Sources disagree on the deadline (after Gascoigne, after reaching the Ward, or before Vicar Amelia). Claim it before Nightfall to be safe; the weapon itself is also sold later.
Point of no return
Examining Laurence's skull after Vicar Amelia moves the world to Night. Before you do, make sure you have started the Young Girl's quest, spoken to Eileen outside Oedon Chapel, cooperated with Alfred and claimed Gilbert's Flamesprayer.
Summary
Talk to Gilbert again once you have reached Cathedral Ward and he gives you his Flamesprayer.
Sources
Report an issue
Eileen: talk to her outside Oedon ChapelQuest stepMissablePoint of no return
Location
Cathedral Ward · Outside Oedon Chapel
Why you can lose it
She leaves this spot at Nightfall, or if you fight Henryk first. Shhh! and the rest of her line depend on this talk.
Point of no return
Examining Laurence's skull after Vicar Amelia moves the world to Night. Before you do, make sure you have started the Young Girl's quest, spoken to Eileen outside Oedon Chapel, cooperated with Alfred and claimed Gilbert's Flamesprayer.
Summary
Take the door straight ahead of the Oedon Chapel lamp and turn left (the Grand Cathedral gates must be open). She warns you about the Tomb and teaches Shhh!
Sources
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Lonely Old Woman: send her to Oedon ChapelQuest stepMissablePoint of no return
Location
Central Yharnam · Her door past the dog kennels
Why you can lose it
Survivors can no longer be sent anywhere once the Blood Moon rises (after Rom).
Point of no return
Killing Rom raises the Blood Moon. From then on no survivor can be sent to a haven, the Hypogean Gaol lamp is dead, and several NPCs change for the rest of the cycle. Before you jump into the lake, make sure Arianna, the Lonely Old Woman, the Narrow Minded Man and Adella are safe, and that Adella has turned on Arianna.
Requires
Summary
Knock again and name Oedon Chapel. Once there she hands out Sedatives.
Sources
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Healing Church Workshop and Abandoned Old Workshop

Behind Oedon Chapel, the workshop tower leads down to a quiet copy of the Hunter's Dream. Before you leave, send Arianna and the man across her alley to safety.
Arianna: send her to Oedon ChapelQuest stepMissablePoint of no return
Location
Cathedral Ward · Foggy alley behind the main gate
Why you can lose it
She can be sent anywhere until the Blood Moon rises; after Rom her window gives no response. One early trophy guide puts the cutoff at Vicar Amelia, which the wikis do not support, but sending her now costs nothing.
Point of no return
Killing Rom raises the Blood Moon. From then on no survivor can be sent to a haven, the Hypogean Gaol lamp is dead, and several NPCs change for the rest of the cycle. Before you jump into the lake, make sure Arianna, the Lonely Old Woman, the Narrow Minded Man and Adella are safe, and that Adella has turned on Arianna.
Requires
Summary
Her window is at the dead end on the far left of the foggy alley behind the Hunter Chief Emblem gate. She asks for a haven once three bosses are dead, at least one of them beyond Central Yharnam; the Blood-starved Beast has covered that by now. Name Oedon Chapel. In the chapel she teaches Curtsy and offers her blood.
Sources
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Narrow Minded Man: send him to Oedon ChapelQuest stepMissablePoint of no return
Location
Cathedral Ward · Window across from Arianna's
Why you can lose it
Survivors can no longer be sent anywhere once the Blood Moon rises (after Rom).
Point of no return
Killing Rom raises the Blood Moon. From then on no survivor can be sent to a haven, the Hypogean Gaol lamp is dead, and several NPCs change for the rest of the cycle. Before you jump into the lake, make sure Arianna, the Lonely Old Woman, the Narrow Minded Man and Adella are safe, and that Adella has turned on Arianna.
Requires
Summary
His window faces Arianna's and he only talks once she has been sent. He does the opposite of what you say, so name Iosefka's Clinic to send him to the chapel.
Sources
Report an issue

Grand Cathedral and Nightfall

Vicar Amelia guards the Grand Cathedral. Examining the skull behind her turns the night darker and closes several early steps.
Eileen: help her against HenrykQuest stepMissablePoint of no return
Location
Tomb of Oedon
Why you can lose it
Entering the Forbidden Woods before Henryk is dead ends Eileen's line. If she dies in this fight, her line ends too.
Point of no return
Stepping into the Forbidden Woods ends Eileen's questline if Henryk is still alive. Finish the Tomb of Oedon fight first (section 7).
Requires
Summary
Go to the Tomb of Oedon from another lamp (the tomb lamp is dead during this event). Henryk attacks and Eileen joins soon after. Keep her alive and avoid hitting her, then talk to her for the Approval gesture.
Sources
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Heir rune (+20%)UpgradeMissablePoint of no return
Location
Tomb of Oedon
Why you can lose it
Henryk is gone if he is not killed before the Forbidden Woods (and at the latest before Rom).
Point of no return
Stepping into the Forbidden Woods ends Eileen's questline if Henryk is still alive. Finish the Tomb of Oedon fight first (section 7).
Requires
Summary
Henryk's drop from the fight above.
Sources
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Hypogean Gaol

Let a Snatcher carry you off to the Gaol. Adella is there, Darkbeast Paarl waits beyond, and the back way leads to Djura's tower.
Adella: send her to Oedon ChapelQuest stepMissablePoint of no return
Location
Hypogean Gaol · Lower level near the cells
Why you can lose it
She must be reached and sent before the Blood Moon, or she is lost with her gesture.
Point of no return
Killing Rom raises the Blood Moon. From then on no survivor can be sent to a haven, the Hypogean Gaol lamp is dead, and several NPCs change for the rest of the cycle. Before you jump into the lake, make sure Arianna, the Lonely Old Woman, the Narrow Minded Man and Adella are safe, and that Adella has turned on Arianna.
Requires
Summary
She is in a nook on the lower level near your cell. Talk to her in church attire, then name Oedon Chapel. There she teaches Church Bow and offers her blood.
Sources
Report an issue
Djura: reach him from behind and spare the beastsQuest stepMissablePoint of no return
Location
Old Yharnam · Djura's tower (from the Church of the Good Chalice side)
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Use Paarl's shortcut into Old Yharnam and climb his tower ladder without attacking anything. Choose to leave the beasts be for the Powder Keg Hunter Badge and the Brush Off Dust gesture. After that, do not hurt any beast he can see.
Sources
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Forbidden Woods

A huge, winding forest behind the password gate. Join the League, gather a fistful of runes, and bring down the Shadows of Yharnam.

Forsaken Castle Cainhurst

A frozen castle reached by carriage from Hemwick. Join the Vilebloods before you help Alfred, so you keep both oaths' rewards.
Alfred: hand him the Unopened SummonsHidden spoiler – activate to revealQuest stepMissablePoint of no returnMinor spoiler
Location
Cathedral Ward · Forbidden Woods gate
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Back at the Forbidden Woods gate, give him the letter for the Wheel Hunter Badge and the Church Bow gesture.
Sources
Report an issue
Alfred: find him in the Queen's chamberHidden spoiler – activate to revealQuest stepMissablePoint of no returnMajor spoiler
Location
Forsaken Castle Cainhurst · Vileblood Queen's chamber
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Return to Cainhurst. He has done what he came for; talk to him for the Roar gesture.
Sources
Report an issue
Queenly FleshHidden spoiler – activate to revealKey itemMissablePoint of no returnMajor spoiler
Location
Forsaken Castle Cainhurst · Throne
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Inspect the throne after Alfred's visit. Keep it: it restores the Queen at the Altar of Despair later (section 16).
Sources
Report an issue
Radiance oath rune (Executioners)Hidden spoiler – activate to revealUpgradeMissablePoint of no returnMajor spoiler
Location
Cathedral Ward · Behind the church to Old Yharnam
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Reload the area a few times. Alfred's body ends up where you first met him behind the church, holding Radiance.
Sources
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Byrgenwerth and Rom

The old college beyond the woods. Killing Rom at the lake below raises the Blood Moon, which changes the whole city.
Oedon Chapel: ask Arianna for her blood until Adella intervenesHidden spoiler – activate to revealQuest stepMissablePoint of no returnMinor spoiler
Location
Cathedral Ward · Oedon Chapel
Why you can lose it
Neither woman gives blood once the Blood Moon rises, so this outcome must happen before Rom.
Point of no return
Killing Rom raises the Blood Moon. From then on no survivor can be sent to a haven, the Hypogean Gaol lamp is dead, and several NPCs change for the rest of the cycle. Before you jump into the lake, make sure Arianna, the Lonely Old Woman, the Narrow Minded Man and Adella are safe, and that Adella has turned on Arianna.
Requires
Summary
This cycle's outcome for the two women. With both in the chapel and no other blood in your pack, take Blood of Arianna, use it, and ask again. After the third one taken while Adella is there (some pages say a fourth), leave and come back: Arianna is gone and Adella's hands are bloody. In NG+ they go to the clinic, and in NG++ Arianna has her child instead.
Sources
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Yahar'gul, Unseen Village

Under the Blood Moon, finish Eileen's hunt, collect the cord from the clinic, and enter Yahar'gul for the key to the Upper Cathedral Ward.
Eileen: talk to her on the Grand Cathedral stepsQuest stepMissablePoint of no return
Location
Cathedral Ward · Grand Cathedral steps
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
She sits wounded at the top of the steps. Talk to her for the Wait gesture.
Sources
Report an issue
Bloody Crow of CainhurstHidden spoiler – activate to revealBossMissablePoint of no returnMinor spoiler
Location
Cathedral Ward · Grand Cathedral
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Go inside alone and kill the hunter waiting there. If Eileen dies while this fight is on, her line ends and her rewards stay on her body.
Sources
Report an issue
Blood Rapture rune (+300)UpgradeMissablePoint of no return
Location
Cathedral Ward
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Dropped by the Bloody Crow of Cainhurst.
Sources
Report an issue
Hunter oath rune (Hunter of Hunters)UpgradeMissablePoint of no return
Location
Cathedral Ward · Grand Cathedral lamp
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Talk to Eileen at the Grand Cathedral lamp after the fight. She gives you the Hunter rune and the Crow Hunter Badge, then leaves for good.
Sources
Report an issue
Older Sister: give her the Red Messenger RibbonQuest stepMissablePoint of no return
Location
Central Yharnam · The Young Girl's window
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
A new girl is at the Young Girl's window under the Blood Moon. Give her the red ribbon.
Sources
Report an issue
Older Sister: the White Messenger RibbonQuest stepMissablePoint of no return
Location
Central Yharnam · Foot of the ladder
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Reload the area. The White Messenger Ribbon is on her body at the foot of the ladder below the window.
Sources
Report an issue
Patches: talk to him on the second floorHidden spoiler – activate to revealQuest stepMissablePoint of no returnMinor spoiler
Location
Lecture Building · 2nd floor
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
From the second-floor lamp, take the ladder by the Church Giant down to his room. Talk face to face for the Beg for Life gesture; either answer to his question gives the rune.
Sources
Report an issue
Anti-Clockwise Metamorphosis rune (+15%)UpgradeMissablePoint of no return
Location
Lecture Building · 2nd floor
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Patches' gift for the talk above.
Sources
Report an issue

Upper Cathedral Ward

The Choir's private grounds above the workshop. Two bosses wait past the Orphanage, and the Altar of Despair can bring a queen back.
Restore the Queen at the Altar of DespairHidden spoiler – activate to revealQuest stepMissablePoint of no returnMajor spoiler
Location
Upper Cathedral Ward · Altar of Despair
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
With Ebrietas dead, offer the Queenly Flesh at the altar. Annalise is back on her throne and the Vileblood oath carries on.
Sources
Report an issue

The Hunter's Nightmare

The Old Hunters begins here, at about level 70 to 80. Clear the Nightmare's streets and blood river, then face Ludwig.
Simon: tell him nightmares are fascinatingQuest stepMissablePoint of no returnDLC: The Old Hunters
Location
Hunter's Nightmare · First shortcut
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
He waits at the first shortcut back to the first lamp. Choose 'Nightmares are fascinating' to move his story on. Never attack him in this cycle.
Sources
Report an issue
Simon: talk to him near the Underground Corpse Pile lampQuest stepMissablePoint of no returnDLC: The Old Hunters
Location
Hunter's Nightmare · Underground Corpse Pile lamp
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
After Ludwig he appears near the new lamp. Exhaust his dialogue.
Sources
Report an issue

Research Hall and Astral Clocktower

The Healing Church's hidden laboratory. Help Saint Adeline three times, wake Laurence when you are ready, and climb to Lady Maria.
Simon: talk to him by the Research Hall lampQuest stepMissablePoint of no returnDLC: The Old Hunters
Location
Research Hall · Lamp
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Once the staircase is raised he appears by the lamp and urges you up the clocktower.
Sources
Report an issue
Adeline: bring her the first Brain FluidQuest stepMissablePoint of no returnDLC: The Old Hunters
Location
Research Hall
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
She is in a ground-floor room reached from the upper floors through the second-floor elevator room. The two calm big-headed patients (one on the central stair platform, one up on the rafters) each give a Brain Fluid. Hand her one; she offers her blood.
Sources
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Adeline: bring her the second Brain FluidQuest stepMissablePoint of no returnDLC: The Old Hunters
Location
Research Hall
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Leave the area (a trip to the Hunter's Dream is the safe way) and come back, then hand over the second fluid. She gives the Balcony Key. Never strike her.
Sources
Report an issue
Adeline: the third Brain FluidHidden spoiler – activate to revealQuest stepMissablePoint of no returnDLC: The Old HuntersMinor spoiler
Location
Research Hall
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Leave and return once more. She has changed; take the last fluid from her and give it back to her.
Sources
Report an issue
Milkweed oath runeUpgradeMissablePoint of no returnDLC: The Old Hunters
Location
Research Hall
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
Adeline's last gift. Equip it before the Fishing Hamlet: a villager there gives a tool only to Milkweed wearers.
Sources
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Fishing Hamlet

The secret behind the clock. Keep Milkweed on, see Simon's story to its end, deal with Brador, and face the Orphan of Kos on the shore.
Accursed BrewSpellMissablePoint of no returnDLC: The Old Hunters
Location
Fishing Hamlet
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
With Milkweed equipped, talk to the friendly fishman, the first villager you meet after leaving the Astral Clocktower.
Sources
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Simon: stay with him at the Lighthouse HutQuest stepMissablePoint of no returnDLC: The Old Hunters
Location
Fishing Hamlet · Lighthouse Hut
Why you can lose it
Only cycle 1 takes this outcome in this guide's plan (NG+ and NG++ choose the other branch), so it is gone once Gehrman ends cycle 1.
Point of no return
Speaking to Gehrman under the great tree ends cycle 1 whatever you answer. Before you do, finish the outcomes only this cycle takes: the Young Girl's ribbons, Djura spared, Eileen's last hunt and the Hunter rune, Alfred's whole quest with Radiance and the Queen's return, Patches' rune, and Simon's and Adeline's stories with Milkweed and the Accursed Brew.
Requires
Summary
He lies dying by the hut. Keep talking until he dies; he leaves Simon's Bowblade and the Underground Cell Inner Chamber Key.
Sources
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The Burning Dream: Honoring Wishes

The workshop burns and Gehrman waits at the great tree. Finish everything this cycle needs, then refuse him.

NG+: Before the Blood Moon

Cycle 2 takes the other branch of each questline. Play the story again; this section lists only what is different, in the order you meet it.
Young Girl: send her to Iosefka's ClinicQuest stepMissablePoint of no returnNG+1
Location
Central Yharnam · Her window
Why you can lose it
Her quest must be started before Nightfall, and she can only be sent before the Blood Moon.
Point of no return
Cycle 2: examining the skull after Vicar Amelia brings Night. Start the Young Girl's quest first.
Summary
Start her quest as before, then name Iosefka's Clinic instead of giving the brooch. The impostor rewards you at the clinic door.
Sources
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Arianna: send her to Iosefka's ClinicQuest stepMissablePoint of no returnNG+1
Location
Cathedral Ward · Foggy alley
Why you can lose it
She can be sent until the Blood Moon; one early guide says Vicar Amelia, so send her before Amelia anyway.
Point of no return
Cycle 2: killing Rom raises the Blood Moon. Before that, send Arianna and every other survivor to the clinic, send the Beggar, and kill the doctor at the clinic.
Summary
Name the clinic when she asks for a haven. She becomes a celestial there.
Sources
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Lonely Old Woman: send her to Iosefka's ClinicQuest stepMissablePoint of no returnNG+1
Location
Central Yharnam
Why you can lose it
Survivors can no longer be sent anywhere once the Blood Moon rises (after Rom).
Point of no return
Cycle 2: killing Rom raises the Blood Moon. Before that, send Arianna and every other survivor to the clinic, send the Beggar, and kill the doctor at the clinic.
Summary
Name the clinic when she agrees to leave.
Sources
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Narrow Minded Man: send him to Iosefka's ClinicQuest stepMissablePoint of no returnNG+1
Location
Cathedral Ward · Window across from Arianna's
Why you can lose it
Survivors can no longer be sent anywhere once the Blood Moon rises (after Rom).
Point of no return
Cycle 2: killing Rom raises the Blood Moon. Before that, send Arianna and every other survivor to the clinic, send the Beggar, and kill the doctor at the clinic.
Summary
He does the opposite of what you say, so name Oedon Chapel to send him to the clinic.
Sources
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Adella: send her to Iosefka's ClinicQuest stepMissablePoint of no returnNG+1
Location
Hypogean Gaol
Why you can lose it
Survivors can no longer be sent anywhere once the Blood Moon rises (after Rom).
Point of no return
Cycle 2: killing Rom raises the Blood Moon. Before that, send Arianna and every other survivor to the clinic, send the Beggar, and kill the doctor at the clinic.
Summary
In church attire, talk to her in the Hypogean Gaol and name the clinic.
Sources
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Suspicious Beggar: send him to Iosefka's ClinicQuest stepMissablePoint of no returnNG+1
Location
Forbidden Woods · Windmill roof
Why you can lose it
He disappears at the Blood Moon if he has been neither sent nor killed.
Point of no return
Cycle 2: killing Rom raises the Blood Moon. Before that, send Arianna and every other survivor to the clinic, send the Beggar, and kill the doctor at the clinic.
Summary
He crouches over a corpse on the windmill roof past the Cannon in the Forbidden Woods. Name the clinic.
Sources
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Iosefka's Clinic: kill the doctor before the Blood MoonHidden spoiler – activate to revealQuest stepMissablePoint of no returnNG+1Minor spoiler
Location
Iosefka's Clinic
Why you can lose it
After the Blood Moon she drops a cord instead, so this outcome needs her dead before Rom.
Point of no return
Cycle 2: killing Rom raises the Blood Moon. Before that, send Arianna and every other survivor to the clinic, send the Beggar, and kill the doctor at the clinic.
Summary
Enter from the Forbidden Woods. She warns you to leave; carry on upstairs and she fights. This cycle she drops a rune instead of a cord.
Sources
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NG+: Yharnam Sunrise

End cycle 2 by accepting Gehrman's offer.

NG++: Final Branches and Childhood's Beginning

Cycle 3 takes the last outcomes, and its four cords open the final ending.
Arianna: send her to Oedon Chapel, and leave Adella where she isQuest stepMissablePoint of no returnNG+2
Location
Cathedral Ward · Foggy alley
Why you can lose it
She can be sent until the Blood Moon; one early guide says Vicar Amelia, so send her before Amelia anyway.
Point of no return
Cycle 3: killing Rom raises the Blood Moon. Send Arianna to the chapel, then the Beggar (and your buffer survivors), before it.
Summary
This cycle Arianna lives to the end of her story. Do not send Adella anywhere, so there is no rivalry in the chapel.
Sources
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Suspicious Beggar: send him to Oedon Chapel, then kill himHidden spoiler – activate to revealQuest stepMissablePoint of no returnNG+2Minor spoiler
Location
Cathedral Ward · Outside Oedon Chapel
Why you can lose it
He disappears at the Blood Moon if he has been neither sent nor killed.
Point of no return
Cycle 3: killing Rom raises the Blood Moon. Send Arianna to the chapel, then the Beggar (and your buffer survivors), before it.
Summary
Send the Old Woman and the Narrow Minded Man to the chapel first. When the Beggar arrives he kills one resident; kill him right after his first victim, or Arianna will eventually be next. He drops the Beast rune again.
Sources
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About this guide

Expect a demanding action game where bosses take practice, and plan for three playthroughs plus deep Chalice Dungeons that are harder than the main story.

Last verified: Oct 29, 2026 · Patch 1.09 · 0 community corrections shipped

Unofficial fan guide. Not affiliated with the publisher.